We are in constant pursuit of breakthroughs that improve patients' lives. We drive innovation daily to make the world a better place. This was Charles Pfizer's initial vision, and it remains true today. Research confirms what we instinctively know: that purpose-driven companies achieve more, are more inventive, draw and keep the best people, and know how to harness the power of those people. Pfizer's purpose—Breakthroughs that transform patients' lives—drives everything we do and reflects our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and reflects the value we strive to bring to patients and society. Our purpose ensures that patients stay at the centre of all we do. We live our purpose by seeking the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to campaign for pro-innovation/pro-patient policies. Every choice we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can flourish.